Sunday, November 25, 2012

DNA Replication Essay

DNA Replication


Using the image above as reference, this is a simple way to memorise the process.

  • Enzyme helicase unwind the parental double helix.
  • The single strand binding proteins stablise the parental DNA
  • The leading strand is synthesised continously in the 5' to 3' direction by DNA polymerase III
  • The lagging strand is synthesised discontinuously. Primase synthesises a short RNA primer to form Okazaki fragment
  • RNA primer is replaced by DNA polymerase I, then DNA ligase joins the Okazaki fragment to the growing strand.

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